FIL1h Antikörper

Produktnummer ABIN5564286

Der Kaninchen Polyklonal anti-FIL1h Antikörper wird verwendet zum Nachweis von FIL1h in Proben von Human. Er wurde validiert für WB und ELISA.

Kurzübersicht für FIL1h Antikörper (ABIN5564286)

Target: FIL1h (Interleukin 1 eta (FIL1h))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FIL1h Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-FIL1h Antikörper

Verwendungszweck: anti-IL-36beta (human), pAb (IN107)

Spezifität: Recognizes human IL-36beta. Does not cross-react with mouse IL-36beta and IL-36gamma.

Keine Kreuzreaktivität: Maus

Kreuzreaktivität (Details): Does not cross-react with mouse IL-36beta and IL-36gamma.

Produktmerkmale: Polyclonal Antibody. Recognizes human IL-36beta. Does not cross-react with mouse IL-36beta and IL-36gamma. Source: Rabbit. Applications: ELISA, WB. Liquid. In PBS containing 10 % glycerol and 0.02 % sodium azide. IL-36alpha (IL-1F6), IL-36beta (IL-1F8) and IL-36gamma (IL-1F9) bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1. IL-36Ra inhibits the production of proinflammatory cytokines, including IL-12, IL-1beta, IL-6, TNF-alpha and IL-23 induced by IL-36 in BMDC and CD4 T cells. Skin and dendritic cells are targets of the IL-36 interleukins leading to a Th1 response. These cytokines may represent potential targets for immune-mediated inflammatory conditions or, alternatively, could be used as adjuvants in vaccination.

Immunogen: Recombinant human IL-36beta.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: In PBS containing 10 % glycerol and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung:

+4°C

-20°C

Stable for at least 1 year after receipt when stored at -20°C.

Haltbarkeit: 12 months

Details zu FIL1h

Target: FIL1h (Interleukin 1 eta (FIL1h))

Andere Bezeichnung: IL-36beta

Hintergrund:

Alternate Names/Synonyms: Interleukin-36beta Interleukin-1 Family Member 8, IL-1F8

Product Description: IL-36alpha (IL-1F6), IL-36beta (IL-1F8) and IL-36gamma (IL-1F9) bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1. IL-36Ra inhibits the production of proinflammatory cytokines, including IL-12, IL-1beta, IL-6, TNF-alpha and IL-23 induced by IL-36 in BMDC and CD4 T cells. Skin and dendritic cells are targets of the IL-36 interleukins leading to a Th1 response. These cytokines may represent potential targets for immune-mediated inflammatory conditions or, alternatively, could be used as adjuvants in vaccination.