IL36A/IL1F6 Antikörper (C-Term)

Produktnummer ABIN6991915

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch IL36A/IL1F6 in WB, ELISA, IF und IHC (p). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für IL36A/IL1F6 Antikörper (C-Term) (ABIN6991915)

Target: IL36A/IL1F6 (IL1F6) (Interleukin 1 Family, Member 6 (IL1F6))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL36A/IL1F6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-IL36A/IL1F6 Antikörper

Bindungsspezifität: C-Term

Spezifität: IL-36A antibody is human specific. IL-36A antibody will not cross-react with IL-36B or IL-36G.

Aufreinigung: IL-36A antibody is affinity chromatography purified via peptide column.

Immunogen: IL-36A antibody was raised against an 11 amino acid peptide near the carboxy terminus of human IL-36A. The immunogen is located within the last 50 amino acids of IL-36A.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IL-36A antibody can be used for detection of IL-36A by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: IL-36A antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: IL-36A antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu IL36A/IL1F6

Target: IL36A/IL1F6 (IL1F6) (Interleukin 1 Family, Member 6 (IL1F6))

Andere Bezeichnung: IL-36A

Hintergrund: IL-36A is is a member of the interleukin 1 cytokine family whose gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2 (1). IL-36A is thought to activate the NF-kappaB pathway through IL-1 receptor family members IL-1RL2 and IL-1RAcP (2). Like the related proteins IL-36B and IL-36G, IL-36A requires post-translational processing for full agonist activity, but the cleavage mechanism is currently unknown (3). The IL-36 cytokines have been suggested to amplify Th1 responses by enhancing proliferation and Th1 polarization of naive CD4+ T cells (4).

Molekulargewicht: Predicted: 17 kDa

Observed: 16 kDa

Gen-ID: 27179

NCBI Accession: NP_055255

UniProt: Q9UHA7

Pathways: Cancer Immune Checkpoints