TRIM24 Antikörper (AA 530-580)

Produktnummer ABIN6991871

Produktdetails anti-TRIM24 Antikörper

Target: TRIM24 (Tripartite Motif Containing 24 (TRIM24))

Bindungsspezifität: AA 530-580

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRIM24 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: At least two isoforms of TRIM24 are known to exist.

Aufreinigung: TRIM24 Antibody is affinity chromatography purified via peptide column.

Immunogen: TRIM24 antibody was raised against a 19 amino acid peptide near the center of human TRIM24. The immunogen is located within amino acids 530 - 580 of TRIM24.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: TRIM24 antibody can be used for detection of TRIM24 by Western blot at 0.5 - 1 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunocytochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: TRIM24 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: TRIM24 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu TRIM24

Target: TRIM24 (Tripartite Motif Containing 24 (TRIM24))

Andere Bezeichnung: TRIM24 (TRIM24 Produkte)

Synonyme: TRIM24 antikoerper, PTC6 antikoerper, RNF82 antikoerper, TF1A antikoerper, TIF1 antikoerper, TIF1A antikoerper, TIF1ALPHA antikoerper, hTIF1 antikoerper, ptc6 antikoerper, rnf82 antikoerper, tf1a antikoerper, tif1 antikoerper, tif1a antikoerper, tif1alpha antikoerper, A130082H20Rik antikoerper, AI447469 antikoerper, D430004I05Rik antikoerper, TIF1-alpha antikoerper, TIF1alpha antikoerper, Tif1a antikoerper, tripartite motif containing 24 antikoerper, transcription intermediary factor 1-alpha antikoerper, tripartite motif containing 24 S homeolog antikoerper, tripartite motif-containing 24 antikoerper, TRIM24 antikoerper, trim24 antikoerper, LOC100548578 antikoerper, trim24.S antikoerper, Trim24 antikoerper

Hintergrund: TRIM24 Antibody: TRIM24 (TIF1), a member of the tripartite motif (TRIM) family, plays a role in the regulation of cell proliferation and apoptosis. TRIM24 localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The TRIM motif includes three zinc-binding domains (RING, B-box type 1 and B-box type 2) and a coiled-coil region. TIF1 mediates transcriptional events by interactions with the AF2 region of several nuclear receptors, such as the estrogen, retinoic acid and vitamin D3 receptors. Defects in TRIM24 are a cause of thyroid papillary carcinoma (TPC).

Molekulargewicht: Predicted: 112, 116

Observed: 108, 1 of 2 isoforms kDa

Gen-ID: 8805

NCBI Accession: NP_056989

UniProt: O15164