TRIM24 Antikörper (AA 530-580)

Produktnummer ABIN6991871

Der Kaninchen Polyklonal Anti-TRIM24 Antikörper wurde für WB, ELISA, IF und ICC validiert. Er ist geeignet, TRIM24 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für TRIM24 Antikörper (AA 530-580) (ABIN6991871)

Target: TRIM24 (Tripartite Motif Containing 24 (TRIM24))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRIM24 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Produktdetails anti-TRIM24 Antikörper

Bindungsspezifität: AA 530-580

Spezifität: At least two isoforms of TRIM24 are known to exist.

Aufreinigung: TRIM24 Antibody is affinity chromatography purified via peptide column.

Immunogen: TRIM24 antibody was raised against a 19 amino acid peptide near the center of human TRIM24. The immunogen is located within amino acids 530 - 580 of TRIM24.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: TRIM24 antibody can be used for detection of TRIM24 by Western blot at 0.5 - 1 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunocytochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: TRIM24 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: TRIM24 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu TRIM24

Target: TRIM24 (Tripartite Motif Containing 24 (TRIM24))

Andere Bezeichnung: TRIM24

Hintergrund: TRIM24 Antibody: TRIM24 (TIF1), a member of the tripartite motif (TRIM) family, plays a role in the regulation of cell proliferation and apoptosis. TRIM24 localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The TRIM motif includes three zinc-binding domains (RING, B-box type 1 and B-box type 2) and a coiled-coil region. TIF1 mediates transcriptional events by interactions with the AF2 region of several nuclear receptors, such as the estrogen, retinoic acid and vitamin D3 receptors. Defects in TRIM24 are a cause of thyroid papillary carcinoma (TPC).

Molekulargewicht: Predicted: 112, 116

Observed: 108, 1 of 2 isoforms kDa

Gen-ID: 8805

NCBI Accession: NP_056989

UniProt: O15164