ULK2 Antikörper (AA 480-530)

Produktnummer ABIN6991859

Der Kaninchen Polyklonal Anti-ULK2-Antikörper wurde für WB, ELISA, IHC (p) und IF validiert. Er ist geeignet, ULK2 in Proben von Human zu detektieren.

Kurzübersicht für ULK2 Antikörper (AA 480-530) (ABIN6991859)

Target: ULK2 (Unc-51 Like Kinase 2 (ULK2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ULK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Produktdetails anti-ULK2 Antikörper

Bindungsspezifität: AA 480-530

Spezifität: At least two isoforms of ULK2 are known to exist, this antibody will detect both isoforms. ULK2 antibody is predicted to not cross-react with ULK1.

Aufreinigung: ULK2 Antibody is affinity chromatography purified via peptide column.

Immunogen: ULK2 antibody was raised against a 17 amino acid peptide near the center of human ULK2 . The immunogen is located within amino acids 480 - 530 of ULK2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ULK2 Antibody can be used for detection of ULK2 by Western blot at 1 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: ULK2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: ULK2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu ULK2

Target: ULK2 (Unc-51 Like Kinase 2 (ULK2))

Andere Bezeichnung: ULK2

Hintergrund: ULK2 Antibody: ULK2, also known as ATG1B, is a key serine/threonine protein kinase probably acting at the most upstream step of autophagosome formation. Knockout of ULK2 results in a severe defect in the autophagy pathway. ULK2 is highly conserved among eukaryotes and shows high homology with its related protein ULK1. Both ULK1 and ULK2 form a complex with ATG13 and FIP200 that mediates TOR signaling and is essential for autophagy. Like ULK1, ULK2 is also thought to be involved in early neuronal growth and differentiation.

Molekulargewicht: Predicted: 105, 114 kDa

Observed: 100 kDa

Gen-ID: 9706

NCBI Accession: NP_055498

UniProt: Q8IYT8

Pathways: Regulation of Cell Size, Autophagie