ULK2 Antikörper (pSer323)

Produktnummer ABIN1881982

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch ULK2 in DB. Es zeigt Reaktivität gegenüber Proben von Human. Es wurde in 3+ Publikationen zitiert.

Kurzübersicht für ULK2 Antikörper (pSer323) (ABIN1881982)

Target: ULK2 (Unc-51 Like Kinase 2 (ULK2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ULK2 Antikörper ist unkonjugiert

Applikation: Dot Blot (DB)

Klon: RB40763

Produktdetails anti-ULK2 Antikörper

Bindungsspezifität: pSer323

Homologie: M

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ULK2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S323 of human ULK2.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: DB: 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-ULK2 Antikörper (ABIN1881982)

Jung, Jun, Ro, Kim, Otto, Cao, Kundu, Kim: "ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery." in: Molecular biology of the cell, Vol. 20, Issue 7, pp. 1992-2003, (2009) (PubMed).

Stelzl, Worm, Lalowski, Haenig, Brembeck, Goehler, Stroedicke, Zenkner, Schoenherr, Koeppen, Timm, Mintzlaff, Abraham, Bock, Kietzmann, Goedde, Toksöz, Droege, Krobitsch, Korn, Birchmeier, Lehrach et al.: "A human protein-protein interaction network: a resource for annotating the proteome. ..." in: Cell, Vol. 122, Issue 6, pp. 957-68, (2005) (PubMed).

Yan, Kuroyanagi, Tomemori, Okazaki, Asato, Matsuda, Suzuki, Ohshima, Mitani, Masuho, Shirasawa, Muramatsu: "Mouse ULK2, a novel member of the UNC-51-like protein kinases: unique features of functional domains." in: Oncogene, Vol. 18, Issue 43, pp. 5850-9, (1999) (PubMed).

Details zu ULK2

Target: ULK2 (Unc-51 Like Kinase 2 (ULK2))

Andere Bezeichnung: ULK2

Hintergrund: This gene encodes a protein that is similar to a serine/threonine kinase in C. elegans which is involved in axonal elongation. The structure of this protein is similar to the C. elegans protein in that both proteins have an N-terminal kinase domain, a central proline/serine rich (PS) domain, and a C-terminal (C) domain. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq].

Molekulargewicht: 112694

NCBI Accession: NP_001136082, NP_055498

UniProt: Q8IYT8

Pathways: Regulation of Cell Size, Autophagie