AGR2 Antikörper (N-Term)

Produktnummer ABIN6991826

Der Kaninchen Polyklonal Anti-AGR2 Antikörper wurde für WB, ELISA, IF und IHC (p) validiert. Er ist geeignet, AGR2 in Proben von Human und Maus zu detektieren.

Kurzübersicht für AGR2 Antikörper (N-Term) (ABIN6991826)

Target: AGR2 (Anterior Gradient Homolog 2 (Xenopus Laevis) (AGR2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AGR2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-AGR2 Antikörper

Bindungsspezifität: N-Term

Spezifität: Two isoforms of AGR2 exists as a result of alternative splicing event.

Aufreinigung: AGR2 Antibody is affinity chromatography purified via peptide column.

Immunogen: Rabbit polyclonal AGR2 antibody was raised against a 17 amino acid peptide near the amino terminus of human AGR2. The immunogen is located within the first 50 amino acids of AGR2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: AGR2 antibody can be used for detection of AGR2 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: AGR2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: AGR2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu AGR2

Target: AGR2 (Anterior Gradient Homolog 2 (Xenopus Laevis) (AGR2))

Andere Bezeichnung: AGR2

Hintergrund: AGR2 Antibody: AGR2 (anterior gradient protein 2) and AGR3 are members of the anterior gradient homolog family. They are secreted cytoplasmic proteins which are involved in metastasis induction and p53 tumour supressor inhibition. They may serve as molecular markers and potential therapeutic targets for hormone-responsive breast tumours. AGR2 is ubiquitously expressed with upregulated expression in prostate cancer, breast cancer, lung cancer, renal carcinomas and endometrial carcinomas. AGR2 expression is positively correlated with that of the estrogen receptor (ER) and is negatively correlated with that of the epidermal growth factor receptor (EGFR).

Molekulargewicht: 19 kDa

Gen-ID: 10551

NCBI Accession: NP_006399

UniProt: O95994