IL15RA Antikörper (AA 40-90)
Kurzübersicht für IL15RA Antikörper (AA 40-90) (ABIN6991821)
Target
Alle IL15RA Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 40-90
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Spezifität
- Multiple isoforms of IL-15RA are known to exist.
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Aufreinigung
- IL-15RA Antibody is affinity chromatography purified via peptide column.
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Immunogen
- Rabbit polyclonal IL-15RA antibody was raised against a 16 amino acid peptide near the center of human IL-15RA. The immunogen is located within amino acids 40 - 90 of IL-15RA.
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Isotyp
- IgG
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Applikationshinweise
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IL-15RA antibody can be used for detection of IL-15RA by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in rat samples. All other applications and species not yet tested. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- IL-15RA Antibody is supplied in PBS containing 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,4 °C
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Informationen zur Lagerung
- IL-15RA antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- IL15RA (Interleukin 15 Receptor, alpha (IL15RA))
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Andere Bezeichnung
- IL-15RA
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Hintergrund
- IL-15RA Antibody: Interleukin 15 (IL-15RA) is a cytokine receptor that specifically binds IL-15 with high affinity. IL-15 regulates T and natural killer cell activation and proliferation. The IL-15 and IL-2 receptors share two subunits, IL-2R beta and IL-2R gamma, and IL-15RA is structurally related to IL-2RA, an additional IL-2-specific alpha subunit necessary for high affinity IL-2 binding. Unlike IL-2RA, IL-15RA is capable of binding IL-15 with high affinity independent of the other subunits. IL-15RA is thought to enhance cell proliferation and expression of apoptosis inhibitor Bcl-xL and Bcl-2.
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Molekulargewicht
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Predicted: 26, 30, 38 kDa
Observed: 30 kDa -
Gen-ID
- 3601
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NCBI Accession
- NP_001243694
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UniProt
- Q13261
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Pathways
- JAK-STAT Signalweg
Target
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