EED Antikörper (N-Term)

Produktnummer ABIN6991742

Der Kaninchen Polyklonal Anti-EED-Antikörper wurde für WB, ELISA und IF validiert. Er ist geeignet, EED in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für EED Antikörper (N-Term) (ABIN6991742)

Target: EED (Embryonic Ectoderm Development (EED))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EED Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Produktdetails anti-EED Antikörper

Bindungsspezifität: AA 30-80, N-Term

Spezifität: Four alternatively spliced transcript variants have been observed.

Aufreinigung: EED Antibody is affinity chromatography purified via peptide column.

Immunogen: EED antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human EED. The immunogen is located within amino acids 30 - 80 of EED.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: EED antibody can be used for detection of EED by Western blot at 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: EED Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: EED antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu EED

Target: EED (Embryonic Ectoderm Development (EED))

Andere Bezeichnung: EED

Hintergrund: EED Antibody: The EED protein (WAIT-1 or WD protein associated with integrin cytoplasmic tails-1), also called embryonic ectoderm development, is a member of the superfamily of WD-40 repeat proteins and widely conserved polycomb group (PcG) family of proteins. The polycomb group (PcG) is a large and evolutionarily conserved set of genes whose products act in multimeric complexes to modify histones, which are then thought to cause stable and heritable states of transcriptional repression. EED shuttles between the nucleus and the plasma membrane and can interact with the cytoplasmic tail of integrin β,7 subunit. EED exerted an antiviral activity at the late stage of HIV-1 replication.

Molekulargewicht: Predicted: 49 kDa

Observed: 49 kDa

Gen-ID: 8726

NCBI Accession: NP_003788

UniProt: O75530