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UCMA Antikörper (C-Term)

UCMA Reaktivität: Human, Maus WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6991131
  • Target Alle UCMA Antikörper anzeigen
    UCMA (Upper Zone of Growth Plate and Cartilage Matrix Associated (UCMA))
    Bindungsspezifität
    • 15
    • 2
    C-Term
    Reaktivität
    Human, Maus
    Wirt
    • 17
    Kaninchen
    Klonalität
    • 17
    Polyklonal
    Konjugat
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser UCMA Antikörper ist unkonjugiert
    Applikation
    • 17
    • 4
    • 4
    • 3
    • 1
    Western Blotting (WB), ELISA
    Aufreinigung
    UCMA Antibody is affinity chromatography purified via peptide column.
    Immunogen
    UCMA antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human UCMA. The immunogen is located within the last 50 amino acids of UCMA.
    Isotyp
    IgG
    Top Product
    Discover our top product UCMA Primärantikörper
  • Applikationshinweise
    UCMA antibody can be used for detection of UCMA by Western blot at 2.5 - 5 μ,g/mL.

    Antibody validated: Western Blot in human samples. All other applications and species not yet tested.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    UCMA Antibody is supplied in PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,4 °C
    Informationen zur Lagerung
    UCMA antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    UCMA (Upper Zone of Growth Plate and Cartilage Matrix Associated (UCMA))
    Andere Bezeichnung
    UCMA (UCMA Produkte)
    Synonyme
    BN antikoerper, GRP-10 antikoerper, preproGRP antikoerper, proGRP antikoerper, grp antikoerper, GRP2 antikoerper, ucma antikoerper, zgc:162317 antikoerper, C10orf49 antikoerper, GRP antikoerper, RGD1308977 antikoerper, 1110017I16Rik antikoerper, AW121955 antikoerper, Grp antikoerper, GRP1 antikoerper, zgc:85838 antikoerper, gastrin releasing peptide antikoerper, upper zone of growth plate and cartilage matrix associated antikoerper, upper zone of growth plate and cartilage matrix associated L homeolog antikoerper, upper zone of growth plate and cartilage matrix associated a antikoerper, upper zone of growth plate and cartilage matrix associated b antikoerper, GRP antikoerper, UCMA antikoerper, ucma.L antikoerper, ucmaa antikoerper, ucma antikoerper, Ucma antikoerper, ucmab antikoerper
    Hintergrund
    UCMA Antibody: UCMA is a secreted cartilage-specific protein that was discovered in a screen for differentially expressed genes in retinoic acid-treated mouse chondrocytes. It was also identified in a human chondrocyte EST screen for candidate genes of skeletal dysplasias. UCMA expression is thought to parallel that of collagen II with its expression decreasing with maturation chrondrocytes mature. UCMA is processed by a furin-like protease into two fragments, an amino-terminal fragment and a carboxy-terminal fragment (UCMA-C). Application of recombinant UCMA-C to primary osteoblasts, mesenchymal stem cells, and MC3T3-E1 pre-osteoblasts interferes with their osteogenic differentiation, but does not affect expression of chondrocyte-specific genes or chondrocyte proliferation, suggesting that UCMA may be involved in the negative control of osteogenic differentiation of osteochondrogenic precursor cells. At least two isoforms of UCMA are known to exist.
    Molekulargewicht
    Predicted: 15 kDa

    Observed: 19 kDa
    Gen-ID
    221044
    NCBI Accession
    NP_660357
    UniProt
    Q8WVF2
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