UCMA Antikörper (AA 21-120) (Cy3)

Produktnummer ABIN1702236

Produktdetails anti-UCMA Antikörper (Cy3)

Target: UCMA (Upper Zone of Growth Plate and Cartilage Matrix Associated (UCMA))

Bindungsspezifität: AA 21-120

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UCMA Antikörper ist konjugiert mit Cy3

Applikation: Western Blotting (WB)

Homologie: Human,Mouse,Rat

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human UCMA

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu UCMA

Target: UCMA (Upper Zone of Growth Plate and Cartilage Matrix Associated (UCMA))

Andere Bezeichnung: UCMA (UCMA Produkte)

Synonyme: BN antikoerper, GRP-10 antikoerper, preproGRP antikoerper, proGRP antikoerper, grp antikoerper, GRP2 antikoerper, ucma antikoerper, zgc:162317 antikoerper, C10orf49 antikoerper, GRP antikoerper, RGD1308977 antikoerper, 1110017I16Rik antikoerper, AW121955 antikoerper, Grp antikoerper, GRP1 antikoerper, zgc:85838 antikoerper, gastrin releasing peptide antikoerper, upper zone of growth plate and cartilage matrix associated antikoerper, upper zone of growth plate and cartilage matrix associated L homeolog antikoerper, upper zone of growth plate and cartilage matrix associated a antikoerper, upper zone of growth plate and cartilage matrix associated b antikoerper, GRP antikoerper, UCMA antikoerper, ucma.L antikoerper, ucmaa antikoerper, ucma antikoerper, Ucma antikoerper, ucmab antikoerper

Hintergrund:

Synonyms: C10orf49, Gla rich protein, Gla-rich protein, Grp, GRP, OTTMUSP00000011599, RP23-272I15.1, UCMA, Ucma-C, UCMA_HUMAN, Unique cartilage matrix associated protein, Unique cartilage matrix-associated protein C-terminal fragment, Upper zone of growth plate and cartilage matrix associated.

Background: UCMA is a 138 amino acid secreted protein that is highly expressed in resting chrondrocytes in developing long bones and is thought to function in the early phase of chrondrocyte differentiation. A furin-like protease processes UCMA into an N-terminal 37 amino acid peptide and a C-terminal 74 amino acid peptide, which is referred to as Unique cartilage matrix-associated protein C-terminal fragment (Ucma-C). Introduction of recombinant Ucma-C interferes with osteogenic differentiation of mesenchymal stem cells, MC3T3-E1 preosteoblasts and primary osteoblasts. This suggests that Ucma may be involved in the negative regulation of osteogenic differentiation of osteochondrogenic precursor cells at the cartilage-bone interface and in peripheral zones of fetal cartilage.

Gen-ID: 221044