RASD2 Antikörper (N-Term)

Produktnummer ABIN6990811

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch RASD2 in WB, ELISA, IF und IHC (p). Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für RASD2 Antikörper (N-Term) (ABIN6990811)

Target: RASD2 (RASD Family, Member 2 (RASD2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RASD2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-RASD2 Antikörper

Bindungsspezifität: AA 20-70, N-Term

Spezifität: TEM2 antibody may cross-react with the closely related protein RASD1.

Aufreinigung: TEM2 Antibody is affinity chromatography purified via peptide column.

Immunogen: TEM2 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of the human TEM2. The immunogen is located within amino acids 20 - 70 of TEM2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: TEM2 antibody can be used for detection of TEM2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in rat samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: TEM2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: TEM2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu RASD2

Target: RASD2 (RASD Family, Member 2 (RASD2))

Andere Bezeichnung: TEM2

Hintergrund: TEM2 Antibody: Rhes, also known as tumor endothelial marker 2 (TEM2), is a small GTP-binding protein that is predominantly expressed in the striatal region of the brain. This protein belongs to the RASD subfamily of Ras-related GTP-binding protein superfamily and is thought to play a role in the normal development and function of the brain as mice lacking this gene showed increased anxiety levels and motor coordination deficits. Rhes was identified as TEM2 through analysis of genes whose expression was upregulated in tumor endothelium. Tumor endothelial markers are significantly up-regulated during angiogenesis and neoangiogenesis that are crucial for the growth of solid tumors. TEMs localized on the cell surface and conserved across species are of particular interest for future development of anti-angiogenic therapies.

Gen-ID: 23551

UniProt: Q96D21