RASD2 Antikörper (C-Term)

Produktnummer ABIN500889

Produktdetails anti-RASD2 Antikörper

Target: RASD2 (RASD Family, Member 2 (RASD2))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RASD2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody detects RASD2 / TEM2 at C-term.

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse, rat

Aufreinigung: Peptide affinity chromatography

Immunogen: TEM2 antibody was raised against a 15 amino acid peptide near the carboxy terminus of the human TEM2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu RASD2

Target: RASD2 (RASD Family, Member 2 (RASD2))

Andere Bezeichnung: RASD2 / TEM2 (RASD2 Produkte)

Synonyme: RASD2 antikoerper, MGC:4834 antikoerper, Rhes antikoerper, TEM2 antikoerper, 4930526B11Rik antikoerper, AU045414 antikoerper, TEM-2 antikoerper, RASD family member 2 antikoerper, RASD family, member 2 antikoerper, RASD2 antikoerper, Rasd2 antikoerper

Hintergrund: Rhes, also known as tumor endothelial marker 2 (TEM2), is a small GTP-binding protein that is predominantly expressed in the striatal region of the brain. This protein belongs to the RASD subfamily of Ras-related GTP-binding protein superfamily and is thought to play a role in the normal development and function of the brain as mice lacking this gene showed increased anxiety levels and motor coordination deficits. Rhes was identified as TEM2 through analysis of genes whose expression was upregulated in tumor endothelium. Tumor endothelial markers are significantly up-regulated during angiogenesis and neoangiogenesis that are crucial for the growth of solid tumors. TEMs localized on the cell surface and conserved across species are of particular interest for future development of anti-angiogenic therapies.Synonyms: GTP-binding protein Rhes, Ras homolog enriched in striatum, Tumor endothelial marker 2

Gen-ID: 23551

UniProt: Q96D21