Stathmin 1 Antikörper (N-Term)

Produktnummer ABIN6990758

Der Kaninchen Polyklonal Anti-Stathmin 1-Antikörper wurde für WB, ELISA, IF und IHC (p) validiert. Er ist geeignet, Stathmin 1 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für Stathmin 1 Antikörper (N-Term) (ABIN6990758)

Target: Stathmin 1 (STMN1)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Stathmin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Stathmin 1 Antikörper

Bindungsspezifität: N-Term

Aufreinigung: op18 Antibody is affinity chromatography purified via peptide column.

Immunogen: Anti-op18 antibody was raised against a peptide corresponding to 17 amino acids near the amino terminus of human op18. The immunogen is located within the first 50 amino acids of op18.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 0.5-2 μ,g/mL, IHC: 2.5 μ,g/mL, IF: 20 μ,g/mL.

Antibody validated: Western Blot in human, mouse and rat samples, Immunohistochemistry and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: op18 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: op18 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu Stathmin 1

Target: Stathmin 1 (STMN1)

Andere Bezeichnung: op18

Hintergrund: Op18 Antibody: Op18 belongs to the stathmin family of genes and encodes a ubiquitous cytosolic phosphoprotein that may function as an intracellular relay integrating several signaling pathways such as those involved in cell proliferation and differentiation. Op18 has also been shown to be involved in the regulation of the microtubule filament system by destabilizing microtubules, thereby preventing assembly and promoting the disassembly of microtubules. More recently, op18 has been implicated as a potential target of the ASK1-p38 MAP kinase cascade, suggesting that the ASK1-p38 cascade may regulate microtubule dynamics through op18. Op18 is highly expressed in a wide variety of human malignancies, including leukemia, prostate cancer, ovarian carcinoma, and breast carcinoma, suggesting that op18 may be an ideal target for anti-cancer therapeutics.

Molekulargewicht: Predicted: 17kD

Observed: 17 kD kDa

Gen-ID: 3925

UniProt: P16949

Pathways: MAPK Signalweg, Microtubule Dynamics