LY86 Antikörper (C-Term)

Produktnummer ABIN6990647

Der Kaninchen Polyklonal Anti-LY86-Antikörper wurde für WB, ELISA und IHC (p) validiert. Er ist geeignet, LY86 in Proben von Human zu detektieren.

Kurzübersicht für LY86 Antikörper (C-Term) (ABIN6990647)

Target: LY86 (Lymphocyte Antigen 86 (LY86))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LY86 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-LY86 Antikörper

Bindungsspezifität: C-Term

Aufreinigung: MD-1 Antibody is affinity chromatography purified via peptide column.

Immunogen: MD-1 antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human MD-1. The immunogen is located within the last 50 amino acids of MD-1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: MD-1 antibody can be used for the detection of MD-1 by Western blot at 0.5 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: MD-1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: MD-1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu LY86

Target: LY86 (Lymphocyte Antigen 86 (LY86))

Andere Bezeichnung: MD-1

Hintergrund: MD-1 Antibody: Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The signaling of these TLRs is kept under tight control by the expression of endogenous inhibiting proteins such as RP105, a recently identified homolog of TLR4. This protein, in association with MD-1, interacts with and inhibits the TLR4/MD-2 signaling pathway. While MD-2 can directly bind to LPS, one of the activating molecules of TLR4, the function of MD-1 is less well-known. It has been suggested however, that the RP105/MD-1 complex influences antibody production mediated by both TLR4/MD-2 and TLR2 receptor complexes.

Gen-ID: 9450

NCBI Accession: NP_004262

UniProt: O95711

Pathways: Toll-Like Receptors Cascades