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CASP5 Antikörper (AA 170-220)

CASP5 Reaktivität: Human, Maus WB, ELISA, ICC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6990517
  • Target Alle CASP5 Antikörper anzeigen
    CASP5 (Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5))
    Bindungsspezifität
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 170-220
    Reaktivität
    • 38
    • 8
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 36
    • 2
    Kaninchen
    Klonalität
    • 28
    • 10
    Polyklonal
    Konjugat
    • 21
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Dieser CASP5 Antikörper ist unkonjugiert
    Applikation
    • 20
    • 13
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
    Spezifität
    Depending on cell lines or tissues used, other cleavage products may be observed.
    Aufreinigung
    Caspase-5 Antibody is affinity chromatography purified via peptide column.
    Immunogen
    Caspase-5 antibody was raised against a 14 amino acid synthetic peptide from the center of human Caspase-5. The immunogen is located within amino acids 170 - 220 of Caspase-5.
    Isotyp
    IgG
    Top Product
    Discover our top product CASP5 Primärantikörper
  • Applikationshinweise
    Casp-5 antibody can be used for the detection of caspase-5 by Western blot at 0.5 - 2 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 2 μ,g/mL. For immunofluorescence start at 2 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunocytochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Caspase-5 Antibody is supplied in PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,4 °C
    Informationen zur Lagerung
    Caspase-5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    CASP5 (Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5))
    Andere Bezeichnung
    Caspase-5 (CASP5 Produkte)
    Hintergrund
    Caspase-5 Antibody: Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. Members of this subfamily include caspase-1, -4, -5, and -12. Activation of these caspases results in the cleavage and activation of proinflammatory cytokines such as IL-1β, and IL-18. Caspase-5 can interact with caspase-1, both are constituents of the NALP1 inflammasome, a complex that can trigger the cleavage of pro-IL-1β,. Expression of caspase-5 can be regulated by lipopolysaccharide (LPS) and IFN-gamma.
    Gen-ID
    838
    UniProt
    P51878
    Pathways
    Inflammasome
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