TLR7 Antikörper (AA 420-470)

Produktnummer ABIN6990451

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch TLR7 in WB, ELISA und ICC. Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für TLR7 Antikörper (AA 420-470) (ABIN6990451)

Target: TLR7 (Toll-Like Receptor 7 (TLR7))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TLR7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Produktdetails anti-TLR7 Antikörper

Bindungsspezifität: AA 420-470

Aufreinigung: TLR7 Antibody is affinity chromatography purified via peptide column.

Immunogen: TLR7 antibody was raised against a peptide corresponding to 14 amino acids near the center of mouse TLR7. The immunogen is located within amino acids 420 - 470 of TLR7.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: TLR7 antibody can be used for detection of TLR7 by Western blot at 0.5 to 2 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 2 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: TLR7 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: TLR7 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu TLR7

Target: TLR7 (Toll-Like Receptor 7 (TLR7))

Andere Bezeichnung: TLR7

Hintergrund: TLR7 Antibody: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. TLR7, like TLRs 3, 8, and 9, is localized in intracellular acidic compartments such as the phagolysosome and will recognize some single-stranded RNA viruses such as vesicular stomatitis virus (VSV) and influenza virus. Activation of TLR7 by VSV results in stimulation of the immune response including IFNalpha secretion, suggesting the importance of TLR7 in virus recognition.

Molekulargewicht: Predicted: 116 kDa

Observed: 135 kDa

Gen-ID: 170743

NCBI Accession: NP_573474

UniProt: P58681

Pathways: TLR Signalweg, Activation of Innate immune Response, Toll-Like Receptors Cascades