Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
Aufreinigung
CARD9 Antibody is affinity chromatography purified via peptide column.
Immunogen
CARD9 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human CARD9. The immunogen is located within the last 50 amino acids of CARD9.
CARD9
Reaktivität: Human
WB, IF, EIA
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
CARD9 antibody can be used for detection of CARD9 by Western blot at 2.5 μ,g/mL. A band at approximately 59 kDa can be detected. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
CARD9 Antibody is supplied in PBS containing 0.02 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C,4 °C
Informationen zur Lagerung
CARD9 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Target
CARD9
(Caspase Recruitment Domain Family, Member 9 (CARD9))
Gm782 antikoerper, card9 antikoerper, CANDF2 antikoerper, hCARD9 antikoerper, caspase recruitment domain family, member 9 antikoerper, caspase recruitment domain family member 9 antikoerper, Card9 antikoerper, CARD9 antikoerper, card9 antikoerper
Hintergrund
CARD9 Antibody: Apoptosis is related to many diseases and development. Cell death signals are transduced by death domain (DD), death effector domain (DED), and caspase recruitment domain (CARD) containing molecules. CARD containing proteins include some caspases, Apaf-1, CARD4, IAPs, RICK, ARC, RAIDD, BCL-10, and ASC. A novel CARD-containing protein was recently identified and designated CARD9, which interacts with the CARD activation domain of BCL-10. CARD9 associates with BCL-10 and forms a complex within cells. CARD9 induces apoptosis and activates NF-κ,B. CARD9 is an upstream activator of BCL-10 and NF-κ,B signaling.