IL1RAP Antikörper (C-Term)

Produktnummer ABIN6990297

Dieses Anti-IL1RAP-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von IL1RAP in WB, ELISA, ICC und IF. Geeignet für Human.

Kurzübersicht für IL1RAP Antikörper (C-Term) (ABIN6990297)

Target: IL1RAP (Interleukin 1 Receptor Accessory Protein (IL1RAP))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL1RAP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Produktdetails anti-IL1RAP Antikörper

Bindungsspezifität: C-Term

Spezifität: This polyclonal antibody has no cross activity to other members in the IL-1 receptor family.

Aufreinigung: IL-1RAcP Antibody is affinity chromatography purified via peptide column.

Immunogen: IL-1RAcP antibody was raised against a 16 amino acid peptide near the carboxy terminus of human IL-1RAcP. The immunogen is located within the last 50 amino acids of IL-1RAcP.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IL-1RAcP antibody can be used for detection of IL-1RAcP by Western blot at 1 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 2 μ,g/mL. For immunofluorescence start at 5 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: IL-1RAcP Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: IL-1RAcP antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu IL1RAP

Target: IL1RAP (Interleukin 1 Receptor Accessory Protein (IL1RAP))

Andere Bezeichnung: IL-1RAcP

Hintergrund: IL-1RAcP Antibody: The pro-inflammatory cytokine IL-1 induced cellular response requires two subunits of its receptor, IL-1 receptor I (IL-1RI) and IL-1 receptor accessory protein (IL-1RAcP). IL-1RAcP forms a complex with IL-1RI in response to IL-1 treatment. The IL-1 receptor-associated kinase (IRAK), which mediates activation of NF-κ,B inducing kinae (NIK) and of NF-κ,B, recruits to the IL-1R complex through IL-1RAcP. IL-1 activation of stress-activated protein kinase and of acid sphingomyelinase also requires IL-1RAcP. Like IL-1RI, IL-1RAcP subunit is essential for IL-1 mediated cellular response. IL-1RAcP is expressed in many tissues.

Molekulargewicht: Predicted: 63 kDa

Observed: 66 kDa

Gen-ID: 3556

NCBI Accession: NP_001161401

UniProt: Q9NPH3

Pathways: NF-kappaB Signalweg, Growth Factor Binding