Dieses Maus Monoklonal-Antikörper erkennt spezifisch LY96 in WB, ELISA, ICC, IF und IHC (p). Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.
MD-2 antibody can be used for detection of MD-2 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2 μ,g/mL.
Antibody validated: Western Blot in recombinnat protein, Immunohistochemistry in human samples, Immunofluorescence in mouse samples. All other applications and species not yet tested.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
MD-2 Monoclonal Antibody is supplied in PBS containing 0.02 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
MD-2 monoclonal antibody can be stored at -20°C, stable for one year.
Target
LY96
(Lymphocyte Antigen 96 (LY96))
Andere Bezeichnung
MD-2
Hintergrund
MD-2 Monoclonal Antibody: MD-2 is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses. TLR4, the major signaling receptor for lipopolysaccharide (LPS), requires the binding of MD-2 to its extracellular region for maximal response to LPS. The specificity of this response is determined by the species of MD-2, e.g., human MD-2 transfected into mouse cells can cause mouse TLR4 to react to LPS analogs that are normally antagonistic to human but not mouse TLR4.