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LY96 Antikörper (AA 2-160)

Dieses Anti-LY96-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von LY96 in WB, ELISA, IF und IHC (p). Geeignet für Human und Maus.
Produktnummer ABIN6990189

Kurzübersicht für LY96 Antikörper (AA 2-160) (ABIN6990189)

Target

Alle LY96 Antikörper anzeigen
LY96 (Lymphocyte Antigen 96 (LY96))

Reaktivität

  • 48
  • 13
  • 5
  • 2
  • 1
  • 1
  • 1
  • 1
Human, Maus

Wirt

  • 41
  • 13
Maus

Klonalität

  • 44
  • 10
Monoklonal

Konjugat

  • 31
  • 10
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser LY96 Antikörper ist unkonjugiert

Applikation

  • 40
  • 15
  • 14
  • 10
  • 6
  • 6
  • 5
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon

9F1B1
  • Bindungsspezifität

    • 8
    • 8
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2-160

    Aufreinigung

    MD-2 Monoclonal Antibody is immunoaffinity chromotography purified IgG.

    Immunogen

    Mouse monoclonal MD-2 antibody was raised against a recombinant protein corresponding to amino acids 2 to 160 of human MD-2.

    Isotyp

    IgG1
  • Applikationshinweise

    MD-2 antibody can be used for detection of MD-2 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    MD-2 Monoclonal Antibody is supplied in PBS containing 0.02 % sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    MD-2 monoclonal antibody can be stored at -20°C, stable for one year.
  • Target

    LY96 (Lymphocyte Antigen 96 (LY96))

    Andere Bezeichnung

    MD-2

    Hintergrund

    MD-2 Monoclonal Antibody: MD-2 is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses. TLR4, the major signaling receptor for lipopolysaccharide (LPS), requires the binding of MD-2 to its extracellular region for maximal response to LPS. The specificity of this response is determined by the species of MD-2, e.g., human MD-2 transfected into mouse cells can cause mouse TLR4 to react to LPS analogs that are normally antagonistic to human but not mouse TLR4.

    Gen-ID

    23643

    NCBI Accession

    NP_056179

    UniProt

    Q9Y6Y9

    Pathways

    TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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