IRF3 Antikörper (pSer386)
Kurzübersicht für IRF3 Antikörper (pSer386) (ABIN6989927)
Target
Alle IRF3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- pSer386
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Verwendungszweck
- Phospho-IRF3(S386) Monoclonal Antibody
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Kreuzreaktivität
- Human
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Aufreinigung
- Purified by Protein A.
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Immunogen
- Synthetic phospho-Peptide corresponding to residues surrounding Ser386 of human IRF3.
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Isotyp
- IgG
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Applikationshinweise
- WB(1:300-5000), IF(ICC)(1:50-200)
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C for 12 months.
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Haltbarkeit
- 12 months
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- IRF3 (Interferon Regulatory Factor 3 (IRF3))
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Andere Bezeichnung
- IRF3
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Hintergrund
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Synonyms: IIAE7 antibody, Interferon regulatory factor 3 antibody, IRF 3 antibody, IRF-3 antibody, IRF3 antibody, IRF3_HUMAN antibody, MGC94729 antibody
Background: This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011].
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Gen-ID
- 3661
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UniProt
- Q14653
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Pathways
- TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades
Target
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