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KDM1B Antikörper (AA 51-150)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch KDM1B in ELISA, IF (cc), IF (p), IHC (p), ICC und IHC (fro). Er zeigt eine Reaktivität gegenüber Maus und Ratte.
Produktnummer ABIN6989407

Kurzübersicht für KDM1B Antikörper (AA 51-150) (ABIN6989407)

Target

Alle KDM1B Antikörper anzeigen
KDM1B (Lysine (K)-Specific Demethylase 1B (KDM1B))

Reaktivität

  • 34
  • 22
  • 17
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Maus, Ratte

Wirt

  • 40
  • 9
Kaninchen

Klonalität

  • 35
  • 14
Polyklonal

Konjugat

  • 19
  • 4
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser KDM1B Antikörper ist unkonjugiert

Applikation

  • 22
  • 21
  • 12
  • 12
  • 9
  • 8
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Bindungsspezifität

    • 14
    • 7
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 51-150

    Kreuzreaktivität

    Maus, Ratte

    Homologie

    Human,Dog,Cow,Sheep,Pig,Horse,Rabbit

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human LSD2 / AOF1

    Isotyp

    IgG
  • Applikationshinweise

    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    Haltbarkeit

    12 months
  • Target

    KDM1B (Lysine (K)-Specific Demethylase 1B (KDM1B))

    Andere Bezeichnung

    LSD2 / AOF1

    Hintergrund

    Synonyms: LSD2 / AOF1, KDM1B, amine oxidase (flavin containing) domain 1, amine oxidase, flavin containing 1, AOF1, bA204B7.3, C6orf193, dJ298J15.2, Flavin-containing amine oxidase domain-containing protein 1, FLJ33898, FLJ34109, FLJ43328, KDM1B, KDM1B_HUMAN, LSD2, lysine (K)-specific demethylase 1B, Lysine-specific demethylase 2, Lysine-specific histone demethylase 1B, Lysine-specific histone demethylase 2.

    Background: Histone demethylase that demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Required for de novo DNA methylation of a subset of imprinted genes during oogenesis. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Demethylates both mono- and di-methylated 'Lys-4' of histone H3. Has no effect on tri-methylated 'Lys-4', mono-, di- or tri-methylated 'Lys-9', mono-, di- or tri-methylated 'Lys-27', mono-, di- or tri-methylated 'Lys-36' of histone H3, or on mono-, di- or tri-methylated 'Lys-20' of histone H4.

    Gen-ID

    221656

    UniProt

    Q8NB78

    Pathways

    Warburg Effekt
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