STIM1 Antikörper (AA 601-685)
Kurzübersicht für STIM1 Antikörper (AA 601-685) (ABIN6989320)
Target
Alle STIM1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 601-685
-
Kreuzreaktivität
- Human, Ratte
-
Homologie
- Mouse,Cow,Sheep,Horse
-
Aufreinigung
- Purified by Protein A.
-
Immunogen
- KLH conjugated synthetic peptide derived from human STIM1
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
-
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 1 μg/μL
-
Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
-
Konservierungsmittel
- ProClin
-
Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
Lagerung
- 4 °C,-20 °C
-
Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
-
Haltbarkeit
- 12 months
-
-
- STIM1 (Stromal Interaction Molecule 1 (STIM1))
-
Andere Bezeichnung
- STIM1
-
Hintergrund
-
Synonyms: GOK, SIM, STIM 1, STIM1, STIM-1, Stim1 stromal interaction molecule 1, STIM1_HUMAN, STIM1L, Stromal interaction molecule 1.
Background: Plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores. Acts as Ca(2+) sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca(2+) depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca(2+) release-activated Ca(2+) (CRAC) channel subunit, TMEM142A/ORAI1.
-
Gen-ID
- 6786
-
UniProt
- Q13586
-
Pathways
- T-Zell Rezeptor Signalweg, BCR Signaling
Target
-