FLIP Antikörper (AA 1-100) (HRP)

Produktnummer ABIN6987992

Der Kaninchen Polyklonal Anti-FLIP-Antikörper wurde für WB, IHC (p) und IHC (fro) validiert. Er ist geeignet, FLIP in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für FLIP Antikörper (AA 1-100) (HRP) (ABIN6987992)

Target: FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FLIP Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-FLIP Antikörper (HRP)

Bindungsspezifität: AA 1-100

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CFLIP

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu FLIP

Target: FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))

Andere Bezeichnung: CFLIP

Hintergrund:

Synonyms: c FLIP, c FLIPL, c FLIPR, c FLIPS, c-FLIP, c-FLIPL, c-FLIPR, c-FLIPS, CASH, CASP8 and FADD like apoptosis regulator, CASP8 and FADD-like apoptosis regulator subunit p12, CASP8AP1, Caspase homolog, Caspase like apoptosis regulatory protein, Caspase related inducer of apoptosis, Caspase-eight-related protein, Caspase-like apoptosis regulatory protein, Casper, Cellular FLICE-like inhibitory protein, CFLA, Cflar, CFLAR_HUMAN, CLARP, FADD like anti apoptotic molecule, FADD-like antiapoptotic molecule 1, FLAME, FLAME-1, FLAME1, FLIP, I FLICE, I-FLICE, Inhibitor of FLICE, MACH-related inducer of toxicity, MRIT, OTTHUMP00000163715, OTTHUMP00000206475, OTTHUMP00000206476, OTTHUMP00000206478, OTTHUMP00000206479, OTTHUMP00000206480, OTTHUMP00000206482, OTTHUMP00000207360, Usurpin, Usurpin beta.

Background: The protein encoded by this gene is a regulator of apoptosis and is structurally similar to caspase-8. However, the encoded protein lacks caspase activity and appears to be itself cleaved into two peptides by caspase-8. Several transcript variants encoding different isoforms have been found for this gene, and partial evidence for several more variants exists. [provided by RefSeq, Feb 2011]

Gen-ID: 8837

UniProt: O15519

Pathways: Apoptose, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development