FLIP Antikörper (N-Term)

Produktnummer ABIN2792098

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch FLIP in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Rind (Kuh), Hund und Pferd.

Kurzübersicht für FLIP Antikörper (N-Term) (ABIN2792098)

Target: FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FLIP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FLIP Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: CFLAR Antibody - N-terminal region

Sequenz: HQVEEALDTD EKEMLLFLCR DVAIDVVPPN VRDLLDILRE RGKLSVGDLA

Homologie: Cow: 100%, Dog: 86%, Horse: 93%, Human: 100%, Mouse: 80%, Rat: 80%

Produktmerkmale: This is a rabbit polyclonal antibody against CFLAR. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CFLAR

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu FLIP

Target: FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))

Andere Bezeichnung: CFLAR

Hintergrund:

Background Information: CFLAR might contribute to the carcinogenesis and aggressiveness of endometrial carcinoma and might be a useful prognostic factor in the tumor. CFLAR is specially overexpressed in colon cancers and it might contribute to carcinogenesis of normal colonic mucosa.

Gene Name: CASP8 and FADD-like apoptosis regulator

Alternative Symbols: CASH, FLIP, MRIT, CLARP, FLAME, cFLIP, Casper, FLAME1, c-FLIP, FLAME-1, I-FLICE, c-FLIPL, c-FLIPR, c-FLIPS, CASP8AP1

Protein Name: CASP8 and FADD-like apoptosis regulator

Molekulargewicht: 55kDa

Gen-ID: 8837

NCBI Accession: NP_003870

UniProt: O15519

Pathways: Apoptose, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development