UMPS Antikörper (AA 351-450) (Cy7)

Produktnummer ABIN6986544

Dieser Anti-UMPS Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von UMPS in WB, IF (cc) und IF (p). Geeignet für Human, Cynomolgus und Rhesusaffen.

Kurzübersicht für UMPS Antikörper (AA 351-450) (Cy7) (ABIN6986544)

Target: UMPS (Uridine Monophosphate Synthetase (UMPS))

Reaktivität: Human, Cynomolgus, Rhesusaffen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UMPS Antikörper ist konjugiert mit Cy7

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-UMPS Antikörper (Cy7)

Bindungsspezifität: AA 351-450

Kreuzreaktivität: Cynomolgus, Human, Rhesusaffen

Homologie: Mouse,Rat,Dog,Cow,Sheep,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human UMPS

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu UMPS

Target: UMPS (Uridine Monophosphate Synthetase (UMPS))

Andere Bezeichnung: UMPS

Hintergrund:

Synonyms: Uridine 5'-monophosphate synthase, UMPS, UMP synthase, Orotate phosphoribosyltransferase, OPRT, OPRTase, ODC, OMPdecase, OK/SW-cl.21

Background: This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants.

Gen-ID: 7372

UniProt: P11172

Pathways: Ribonucleoside Biosynthetic Process