UMPS Antikörper (C-Term)

Produktnummer ABIN2783243

Zitiert in 1 Publikation. Der Kaninchen Polyklonal anti-UMPS Antikörper (ABIN2783243) detektiert spezifisch UMPS in WB und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Kaninchen, Meerschweinchen, Pferd, Hund, Rind (Kuh), Schwein und Saccharomyces cerevisiae.

Kurzübersicht für UMPS Antikörper (C-Term) (ABIN2783243)

Target: UMPS (Uridine Monophosphate Synthetase (UMPS))

Reaktivität: Human, Maus, Ratte, Kaninchen, Meerschweinchen, Pferd, Hund, Rind (Kuh), Schwein, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UMPS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-UMPS Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: UMPS Antibody - C-terminal region

Sequenz: VGFISGSRVS MKPEFLHLTP GVQLEAGGDN LGQQYNSPQE VIGKRGSDII

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 93%, Yeast: 75%

Produktmerkmale: This is a rabbit polyclonal antibody against UMPS. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human UMPS

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP48147-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-UMPS Antikörper (ABIN2783243)

Ishikawa, Kondo, Yamaguchi, Sakamoto, Fujisawa: "Effect of varicocelectomy on patients with unobstructive azoospermia and severe oligospermia." in: BJU international, Vol. 101, Issue 2, pp. 216-8, (2008) (PubMed).

Details zu UMPS

Target: UMPS (Uridine Monophosphate Synthetase (UMPS))

Andere Bezeichnung: UMPS

Hintergrund:

Background Information: OPRT (UMPS) is involved in early events of pancreatic and gallbladder carcinogenesis and invasion of hepatocellular carcinomas. Orotate phosphoribosyltransferase is involved in the invasion and metastasis of colorectal carcinoma. Determination of OPRT levels in gastric carcinoma tissue enables to predict the response to S-1-based neoadjuvant/adjuvant chemotherapy.

Gene Name: Uridine monophosphate synthetase

Alternative Symbols: OPRT

Protein Name: Uridine 5'-monophosphate synthase

Molekulargewicht: 52kDa

Gen-ID: 7372

NCBI Accession: NP_000364

UniProt: P11172

Pathways: Ribonucleoside Biosynthetic Process