UMPS Antikörper (AA 351-450)

Produktnummer ABIN5675133

Produktdetails anti-UMPS Antikörper

Target: UMPS (Uridine Monophosphate Synthetase (UMPS))

Bindungsspezifität: AA 351-450

Reaktivität: Human, Cynomolgus, Rhesusaffen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UMPS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Cynomolgus, Human, Rhesusaffen

Homologie: Mouse,Rat,Dog,Cow,Sheep,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human UMPS

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu UMPS

Target: UMPS (Uridine Monophosphate Synthetase (UMPS))

Andere Bezeichnung: UMPS (UMPS Produkte)

Synonyme: zgc:55702 antikoerper, zgc:55723 antikoerper, UMPS antikoerper, OPRT antikoerper, 1700095D23Rik antikoerper, AA408257 antikoerper, AL033308 antikoerper, BB164745 antikoerper, Orotidine 5'-phosphate decarboxylase antikoerper, uridine monophosphate synthetase antikoerper, uridine monophosphate synthetase L homeolog antikoerper, uridine 5'-monophosphate synthase antikoerper, umps-1 antikoerper, umps antikoerper, umps.L antikoerper, UMPS antikoerper, LOC100556619 antikoerper, Umps antikoerper

Hintergrund:

Synonyms: Uridine 5'-monophosphate synthase, UMPS, UMP synthase, Orotate phosphoribosyltransferase, OPRT, OPRTase, ODC, OMPdecase, OK/SW-cl.21

Background: This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants.

Gen-ID: 7372

UniProt: P11172

Pathways: Ribonucleoside Biosynthetic Process