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KDM1B Antikörper (AA 51-150) (AbBy Fluor® 488)

Dieses Anti-KDM1B-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von KDM1B in IF (cc) und IF (p). Geeignet für Maus und Ratte.
Produktnummer ABIN6978018

Kurzübersicht für KDM1B Antikörper (AA 51-150) (AbBy Fluor® 488) (ABIN6978018)

Target

Alle KDM1B Antikörper anzeigen
KDM1B (Lysine (K)-Specific Demethylase 1B (KDM1B))

Reaktivität

  • 34
  • 22
  • 17
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Maus, Ratte

Wirt

  • 40
  • 9
Kaninchen

Klonalität

  • 35
  • 14
Polyklonal

Konjugat

  • 20
  • 4
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser KDM1B Antikörper ist konjugiert mit AbBy Fluor® 488

Applikation

  • 22
  • 22
  • 12
  • 12
  • 9
  • 8
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Bindungsspezifität

    • 14
    • 7
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 51-150

    Kreuzreaktivität

    Maus, Ratte

    Homologie

    Human,Dog,Cow,Sheep,Pig,Horse,Rabbit

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human LSD2 / AOF1

    Isotyp

    IgG
  • Applikationshinweise

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    KDM1B (Lysine (K)-Specific Demethylase 1B (KDM1B))

    Andere Bezeichnung

    LSD2 / AOF1

    Hintergrund

    Synonyms: LSD2 / AOF1, KDM1B, amine oxidase (flavin containing) domain 1, amine oxidase, flavin containing 1, AOF1, bA204B7.3, C6orf193, dJ298J15.2, Flavin-containing amine oxidase domain-containing protein 1, FLJ33898, FLJ34109, FLJ43328, KDM1B, KDM1B_HUMAN, LSD2, lysine (K)-specific demethylase 1B, Lysine-specific demethylase 2, Lysine-specific histone demethylase 1B, Lysine-specific histone demethylase 2.

    Background: Histone demethylase that demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Required for de novo DNA methylation of a subset of imprinted genes during oogenesis. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Demethylates both mono- and di-methylated 'Lys-4' of histone H3. Has no effect on tri-methylated 'Lys-4', mono-, di- or tri-methylated 'Lys-9', mono-, di- or tri-methylated 'Lys-27', mono-, di- or tri-methylated 'Lys-36' of histone H3, or on mono-, di- or tri-methylated 'Lys-20' of histone H4.

    Gen-ID

    221656

    UniProt

    Q8NB78

    Pathways

    Warburg Effekt
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