FASL Antikörper

Produktnummer ABIN6961471

Dieses Anti-FASL-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von FASL in FACS und Func. Geeignet für Human.

Kurzübersicht für FASL Antikörper (ABIN6961471)

Target: FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser FASL Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Functional Studies (Func)

Klon: NOK-1

Produktdetails anti-FASL Antikörper

Aufreinigung: This monoclonal antibody preparation was purified from tissue culture supernatant via affinity chromatography. For In Vivo Ready™ (IVR) products, each preparation is also evaluated for endotoxin levels using the LAL assay. It is recommended to store the product undiluted at 4°C. Do not freeze.

Endotoxin-Niveau: Low endotoxin: < 0.01 EU/ug

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: This antibody preparation has been quality-tested for flow cytometry using an appropriate cell type. The amount of antibody required for optimal staining of a cell sample should be determined empirically in your system. Tonbo Biosciences tests all of our antibodies by flow cytometry. Citations may be provided as a resource for additional applications that have not been validated by Tonbo Biosciences.

Kommentare:

2.0 mg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 10 mM NaH2PO4, 150 mM NaCl, pH 7.2

Konservierungsmittel: Azide free

Lagerung: 4 °C

Informationen zur Lagerung: 2-8°C

Haltbarkeit: 12 months

Details zu FASL

Target: FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))

Andere Bezeichnung: CD178 (Fas ligand)

Hintergrund: The NOK-1 antibody reacts with human CD178 (Fas ligand) in both membrane bound and soluble forms. Fas ligand is a 40 kDa transmembrane glycoprotein, a member of the TNF family, and is expressed by activated T and NK cells, neutrophils, and monocytes. Interactions between CD178 (Fas ligand) and CD95 (Fas) induce a program of apoptosis and play a key role in immune regulation and homeostasis. The extracellular domain of human CD178 can be cleaved from the surface by matrix metalloproteinases (MMPs) resulting in a 26 kDa soluble protein.

Gen-ID: 356

UniProt: P48023

Pathways: Apoptose, EGFR Signaling Pathway, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity