NCOR1 Antikörper
Kurzübersicht für NCOR1 Antikörper (ABIN6952398)
Target
Alle NCOR1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Spezifität
- Polyclonal antibody raised in rabbit against human NCOR1 (Nuclear Receptor Corepressor 1), using a synthetic peptide containing a sequence from the central part of the protein
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Kreuzreaktivität
- Maus
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Aufreinigung
- Affinity purified
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Immunogen
- synthetic peptide
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Applikationshinweise
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ChIP/ChIP-seq 2 μg:ChIP
WB 1:5,000
IP 6 μg:IP -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.2 μg/μL
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Buffer
- TBS, 0,1 % BSA, 0.05 % azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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- NCOR1 (Nuclear Receptor Co-Repressor 1 (NCOR1))
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Andere Bezeichnung
- NCOR1
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Hintergrund
- NCOR1 (UniProtKB/Swiss-Prot entry O75376) mediates transcriptional repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. NCOR1 is part of a complex which may impede the access of basal transcription factors.by promoting histone deacetylation and the formation of repressive chromatin structures.
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UniProt
- O75376
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Pathways
- Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process
Target
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