Cadherin-16 Antikörper

Produktnummer ABIN6950867

Der Maus Monoklonal anti-Cadherin-16 Antikörper (ABIN6950867) detektiert spezifisch Cadherin-16 in IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für Cadherin-16 Antikörper (ABIN6950867)

Target: Cadherin-16 (CDH16)

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Cadherin-16 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Produktdetails anti-Cadherin-16 Antikörper

Verwendungszweck: KSP-Cadherin mouse mAb

Spezifität: The antibody can specifically recognize human KSP-Cadherin protein.

Aufreinigung: The antibody was purified by affinity chromatography using a specific immunogen.

Immunogen: A synthetic peptide corresponding to the amino acid region 1 - 100 of the human KSP - Cadherin protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC, 1:200-1:400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at-20°C. Avoid freeze / thaw cycles.

Details zu Cadherin-16

Target: Cadherin-16 (CDH16)

Andere Bezeichnung: KSP-Cadherin

Hintergrund:

Synonyms: Cadherin-16 (Kidney-specific cadherin, Ksp-cadherin)

Background: KSP-cadherin, also known as cadherin-16, is a new member of the calcium adhesion molecule family and plays an important role during embryonic development. It was specifically expressed in kidney, only in renal tubular epithelium, basement membrane and collecting duct epithelium, but not in glomerulus, renal interstitial cells and blood vessels. The loss of these adhesion molecules in renal cell tumors may be related to tumor dedifferentiation and lymph node metastasis. KSP-cadherin has a sensitivity of up to 100 % in renal chromophobe cell carcinoma and 95 % in renal eosinophilic adenoma.

Gene Name: CDH16 UNQ695/PRO1340

Protein Name: KSP-Cadherin

Gen-ID: 1014

UniProt: O75309