P4HB Antikörper
-
- Target Alle P4HB Antikörper anzeigen
- P4HB (Prolyl 4-Hydroxylase, beta Polypeptide (P4HB))
-
Reaktivität
- Human, Maus, Ratte
-
Wirt
- Kaninchen
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser P4HB Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), Flow Cytometry (FACS)
- Kreuzreaktivität
- Human, Maus, Ratte
- Aufreinigung
- Purified by Protein A.
- Immunogen
- Human PD1 between 1 to 200 amino acids
- Klon
- 6C9
- Isotyp
- IgG
- Top Product
- Discover our top product P4HB Primärantikörper
-
anti-Prolyl 4-Hydroxylase, beta Polypeptide (P4HB) (AA 1-508) antibody
P4HB Reaktivität: Human WB, IP, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Prolyl 4-Hydroxylase, beta Polypeptide (P4HB) antibodyP4HB Reaktivität: Human WB, IF, ICC, IHC (p), IEM Wirt: Kaninchen Polyclonal unconjugated
anti-Prolyl 4-Hydroxylase, beta Polypeptide (P4HB) antibodyP4HB Reaktivität: Human WB, IHC, FACS Wirt: Kaninchen Polyclonal unconjugated
anti-Prolyl 4-Hydroxylase, beta Polypeptide (P4HB) (N-Term) antibodyP4HB Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Kaninchen, Pferd WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Prolyl 4-Hydroxylase, beta Polypeptide (P4HB) (AA 329-508) antibodyP4HB Reaktivität: Human WB, IHC, IP, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Prolyl 4-Hydroxylase, beta Polypeptide (P4HB) (AA 1-508) antibodyP4HB Reaktivität: Human WB, IF Wirt: Maus Polyclonal unconjugated
anti-Prolyl 4-Hydroxylase, beta Polypeptide (P4HB) (AA 409-509) antibodyP4HB Reaktivität: Ratte WB, IHC, IP, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Prolyl 4-Hydroxylase, beta Polypeptide (P4HB) (C-Term) antibodyP4HB Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Schwein, Kaninchen, Pferd WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Prolyl 4-Hydroxylase, beta Polypeptide (P4HB) (AA 436-464), (C-Term) antibodyP4HB Reaktivität: Human WB, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB20830 unconjugated
anti-Prolyl 4-Hydroxylase, beta Polypeptide (P4HB) (AA 409-509) antibody (Alkaline Phosphatase (AP))P4HB Reaktivität: Ratte WB, IHC, IP, IF, ICC Wirt: Kaninchen Polyclonal Alkaline Phosphatase (AP)
-
- Applikationshinweise
-
WB 1:300-5000
FCM 1:20-100 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C for 12 months.
- Haltbarkeit
- 12 months
-
- Target
- P4HB (Prolyl 4-Hydroxylase, beta Polypeptide (P4HB))
- Andere Bezeichnung
- PDI (P4HB Produkte)
- Hintergrund
-
Synonyms: Protein disulfide-isomerase A2, PDIp, Pdia2
Background: This multifunctional protein catalyzes the formation, breakage and rearrangement of disulfide bonds. At the cell surface, seems to act as a reductase that cleaves disulfide bonds of proteins attached to the cell. May therefore cause structural modifications of exofacial proteins. Inside the cell, seems to form/rearrange disulfide bonds of nascent proteins. At high concentrations, functions as a chaperone that inhibits aggregation of misfolded proteins. At low concentrations, facilitates aggregation (anti-chaperone activity). May be involved with other chaperones in the structural modification of the TG precursor in hormone biogenesis. Also acts a structural subunit of various enzymes such as prolyl 4-hydroxylase and microsomal triacylglycerol transfer protein MTTP. Receptor for LGALS9, the interaction retains P4HB at the cell surface of Th2 T helper cells, increasing disulfide reductase activity at the plasma membrane, altering the plasma membrane redox state and enhancing cell migration (PubMed:21670307).
- Gen-ID
- 5034
- UniProt
- P07237
- Pathways
- Maintenance of Protein Location, Cell RedoxHomeostasis, Lipid Metabolism
-
