PARP1 Antikörper (AA 551-620)

Produktnummer ABIN6944423

Dieses Anti-PARP1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von PARP1 in WB, ELISA, ICC, IHC (p), IF (p), IF (cc) und IHC (fro). Geeignet für Human.

Kurzübersicht für PARP1 Antikörper (AA 551-620) (ABIN6944423)

Target: PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PARP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-PARP1 Antikörper

Bindungsspezifität: AA 551-620

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Cow,Sheep,Pig,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PARP1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu PARP1

Target: PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))

Andere Bezeichnung: PARP1

Hintergrund:

Synonyms: ADP ribosyltransferase (NAD+, poly (ADP ribose) polymerase), ADP ribosyltransferase NAD+, ADPRT 1, ADPRT, ADPRT1, msPARP, NAD(+) ADP ribosyltransferase 1, pADPRT 1, pADPRT1, PARP 1, PARP1, PARP-1, Poly (ADP ribose) polymerase 1, poly (ADP ribose) polymerase family, member 1, Poly adenosine diphosphate ADP ribose polymerase, Poly ADP ribose polymerase 1, Poly ADP ribose polymerase family member 1, Poly ADP ribose synthetase 1, poly(ADP ribose) synthetase, poly(ADP ribosyl)transferase, Poly[ADP ribose] synthetase 1, PPOL, sPARP 1, sPARP1, PARP1_HUMAN.

Background: This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008].

Gen-ID: 142

UniProt: P09874

Pathways: Apoptose, Caspase Kaskade in der Apoptose, DNA Reparatur, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location