NEFL Antikörper (AA 31-130) (AbBy Fluor® 594)

Produktnummer ABIN6944272

Der Kaninchen Polyklonal Anti-NEFL-Antikörper wurde für IF (p) und IF (cc) validiert. Er ist geeignet, NEFL in Proben von Ratte und Maus zu detektieren.

Kurzübersicht für NEFL Antikörper (AA 31-130) (AbBy Fluor® 594) (ABIN6944272)

Target: NEFL (Neurofilament, Light Polypeptide (NEFL))

Reaktivität: Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NEFL Antikörper ist konjugiert mit AbBy Fluor® 594

Applikation: Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Produktdetails anti-NEFL Antikörper (AbBy Fluor® 594)

Bindungsspezifität: AA 31-130

Spezifität: SNDLKSIRTQEK-Y 80-91/543

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Cow,Sheep,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NF-L

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu NEFL

Target: NEFL (Neurofilament, Light Polypeptide (NEFL))

Andere Bezeichnung: NF-L

Hintergrund:

Synonyms: Neurofilament L, Neurofilament 68, Neurofilament triplet L, 70 kD Neurofilament Light, 68 kDa neurofilament protein, CMT 1F, CMT 2E, CMT1F, CMT2E, FLJ53642, Light molecular weight neurofilament protein, NEFL, Neurofilament light, Neurofilament light polypeptide 68 kDa, Neurofilament light polypeptide, Neurofilament protein, light chain, Neurofilament subunit NF L, Neurofilament triplet L protein, NF 68, NF L, NF68, NFL, NFL_HUMAN.

Background: Neurofilament light polypeptide also called NF-L, Neurofilament triplet L protein, 68 kDa neurofilament protein. Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. The extra mass and high charge density that distinguish the neurofilament proteins from all other intermediate filament proteins are due to the tailpiece extensions. This region may form a charged scaffolding structure suitable for interaction with other neuronal components or ions. NF-L is the most abundant of the three neurofilament proteins and, as the other nonepithelial intermediate filament proteins, it can form homopolymeric 10-nm filaments. Belongs to the intermediate filament family.

Gen-ID: 4747

UniProt: P07196