NEUROD1 Antikörper (pSer274)

Produktnummer ABIN6944261

Dieser Anti-NEUROD1-Antikörper ist ein Kaninchen-Polyklonal-Antikörper zum Nachweis von NEUROD1 in WB, ELISA, IF (cc), IF (p), IHC (p), ICC und IHC (fro). Geeignet für Human, Maus und Ratte.

Kurzübersicht für NEUROD1 Antikörper (pSer274) (ABIN6944261)

Target: NEUROD1 (Neuronal Differentiation 1 (NEUROD1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NEUROD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-NEUROD1 Antikörper

Bindungsspezifität: pSer274

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Cow,Sheep,Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthesized phosphopeptide derived from human NeuroD1 around the phosphorylation site of Serine 274

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu NEUROD1

Target: NEUROD1 (Neuronal Differentiation 1 (NEUROD1))

Andere Bezeichnung: NeuroD1

Hintergrund:

Synonyms: NeuroD1 (phospho S274), p-NeuroD1 (phospho S274), atonal, basic helix loop helix transcription factor, BETA 2, Beta cell E box transactivator 2, BETA2, BHF 1, BHF1, bHLHa3, class A basic helix loop helix protein 3, Class A basic helix-loop-helix protein 3, MODY 6, MODY6, NDF1_HUMAN, NEUROD, NeuroD1, Neurogenic differentiation 1, Neurogenic differentiation factor 1, neurogenic helix loop helix protein NEUROD, NIDDM.

Background: This gene encodes a member of the NeuroD family of basic helix-loop-helix (bHLH) transcription factors. The protein forms heterodimers with other bHLH proteins and activates transcription of genes that contain a specific DNA sequence known as the E-box. It regulates expression of the insulin gene, and mutations in this gene result in type II diabetes mellitus.

Gen-ID: 4760

UniProt: Q13562

Pathways: Dopaminergic Neurogenesis, Hormone Transport, Carbohydrate Homeostasis