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NEUROD1 Antikörper (N-Term)

NEUROD1 Reaktivität: Human WB, IF, IHC (p) Wirt: Kaninchen Polyclonal RB02901 unconjugated
Produktnummer ABIN388765
  • Target Alle NEUROD1 Antikörper anzeigen
    NEUROD1 (Neuronal Differentiation 1 (NEUROD1))
    Bindungsspezifität
    • 17
    • 16
    • 10
    • 10
    • 8
    • 8
    • 6
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 15-45, N-Term
    Reaktivität
    • 83
    • 62
    • 51
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 94
    • 7
    Kaninchen
    Klonalität
    • 86
    • 15
    Polyklonal
    Konjugat
    • 41
    • 8
    • 8
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser NEUROD1 Antikörper ist unkonjugiert
    Applikation
    • 85
    • 51
    • 26
    • 26
    • 20
    • 17
    • 15
    • 11
    • 8
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This NeuroD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-45 amino acids from the N-terminal region of human NeuroD1.
    Klon
    RB02901
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product NEUROD1 Primärantikörper
  • Applikationshinweise
    IF: 1:10~50. IF: 1:100. WB: 1:1000. IHC-P: 1:50~100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Target
    NEUROD1 (Neuronal Differentiation 1 (NEUROD1))
    Andere Bezeichnung
    NeuroD1 (NEUROD1 Produkte)
    Synonyme
    BETA2 antikoerper, BHF-1 antikoerper, MODY6 antikoerper, NEUROD antikoerper, bHLHa3 antikoerper, Neurod antikoerper, neurod antikoerper, XNeuroD antikoerper, MGC82572 antikoerper, NEUROD1 antikoerper, ND1 antikoerper, beta2 antikoerper, bhf-1 antikoerper, neuro-D antikoerper, nrd antikoerper, neuroD antikoerper, neurod1 antikoerper, Beta2 antikoerper, neuronal differentiation 1 antikoerper, neurogenic differentiation 1 antikoerper, neuronal differentiation 1 S homeolog antikoerper, neuronal differentiation 1 L homeolog antikoerper, NEUROD1 antikoerper, Neurod1 antikoerper, neurod1.S antikoerper, neurod1 antikoerper, neurod1.L antikoerper
    Hintergrund
    NeuroD1 acts as a differentiation factor during neurogenesis. They are expressed transiently in a subset of neurons in the central and peripheral nervous systems at the time of their terminal differentiation. NeuroD1 is a basic helix-loop-helix (bHLH) protein contain 1 bHLH domain. NeuroD1 is a transcriptional activator, for efficient DNA binding it requires dimerization with another bHLH protein. It was reported that NeuroD1 involves heterodimerization with the ubiquitous bHLH protein E47, and regulates insulin gene expression by binding to a critical E-box motif on the insulin promoter. Defects in NEUROD1 causes maturity onset diabetes of the young type VI. MODY6 is a form of non-insulin-dependent diabetes mellitus (NIDDM) characterized by an autosomal dominant mode of inheritance, onset during young adulthood and a primary defect in insulin secretion.
    Molekulargewicht
    39920
    Gen-ID
    4760
    NCBI Accession
    NP_002491
    UniProt
    Q13562
    Pathways
    Dopaminergic Neurogenesis, Hormone Transport, Carbohydrate Homeostasis
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