NEUROD1 Antikörper (AA 26-91)
Kurzübersicht für NEUROD1 Antikörper (AA 26-91) (ABIN1724757)
Target
Alle NEUROD1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 26-91
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Verwendungszweck
- Neurod Antibody
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Aufreinigung
- Ascitic fluid
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Immunogen
- Purified recombinant fragment of human Neurod (AA: 26-91 ) expressed in E. Coli.
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Isotyp
- IgG1
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Applikationshinweise
- ELISA: 1/10000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Ascitic fluid containing 0.03 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "The neuronal differentiation factor NeuroD1 downregulates the neuronal repellent factor Slit2 expression and promotes cell motility and tumor formation of neuroblastoma." in: Cancer research, Vol. 71, Issue 8, pp. 2938-48, (2011) (PubMed).
: "Neurogenic differentiation 1 directs differentiation of cytokeratin 19-positive human pancreatic nonendocrine cells into insulin-producing cells." in: Transplantation proceedings, Vol. 42, Issue 6, pp. 2071-4, (2010) (PubMed).
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- NEUROD1 (Neuronal Differentiation 1 (NEUROD1))
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Andere Bezeichnung
- Neurod
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Hintergrund
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This gene encodes a member of the NeuroD family of basic helix-loop-helix (bHLH) transcription factors. The protein forms heterodimers with other bHLH proteins and activates transcription of genes that contain a specific DNA sequence known as the E-box. It regulates expression of the insulin gene, and mutations in this gene result in type II diabetes mellitus.
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Molekulargewicht
- 40 kDa
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UniProt
- Q13562
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Pathways
- Dopaminergic Neurogenesis, Hormone Transport, Carbohydrate Homeostasis
Target
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