LIG4 Antikörper
Kurzübersicht für LIG4 Antikörper (ABIN6943923)
Target
Alle LIG4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Kreuzreaktivität
- Human
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Aufreinigung
- Purified by Protein A.
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Immunogen
- Recombinant protein within human DNA Ligase IV aa 500-700
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Isotyp
- IgG
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anti-Ligase IV, DNA, ATP-Dependent (LIG4) antibody
KD Validated LIG4 Reaktivität: Human WB, FACS Wirt: Kaninchen Monoclonal 23GB2515 unconjugated Recombinant Antibody
anti-Ligase IV, DNA, ATP-Dependent (LIG4) (AA 612-911) antibodyLIG4 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Ligase IV, DNA, ATP-Dependent (LIG4) (C-Term) antibodyLIG4 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Ligase IV, DNA, ATP-Dependent (LIG4) (N-Term) antibodyLIG4 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Meerschweinchen, Kaninchen WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Ligase IV, DNA, ATP-Dependent (LIG4) antibodyKO Validated LIG4 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Ligase IV, DNA, ATP-Dependent (LIG4) (AA 802-911) antibodyLIG4 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 2D2 unconjugated
anti-Ligase IV, DNA, ATP-Dependent (LIG4) (AA 275-324) antibodyLIG4 Reaktivität: Human, Pferd, Affe WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Ligase IV, DNA, ATP-Dependent (LIG4) (N-Term) antibodyLIG4 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Ligase IV, DNA, ATP-Dependent (LIG4) (Center) antibodyLIG4 Reaktivität: Human, Rind (Kuh), Hund WB, IHC, IF, IC Wirt: Kaninchen Polyclonal unconjugated
anti-Ligase IV, DNA, ATP-Dependent (LIG4) antibodyLIG4 Reaktivität: Human, Maus IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
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WB 1:300-5000
IHC-P 1:200-400 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Haltbarkeit
- 12 months
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- LIG4 (Ligase IV, DNA, ATP-Dependent (LIG4))
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Andere Bezeichnung
- LIG4
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Hintergrund
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Synonyms: DNA ligase 4, DNA ligase IV, Polydeoxyribonucleotide synthase [ATP] 4, LIG4.
Background: Efficiently joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.
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Gen-ID
- 3981
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UniProt
- P49917
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Pathways
- DNA Reparatur, Production of Molecular Mediator of Immune Response
Target
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