Rekombinanter DUSP6 Antikörper (AA 1-350)

Produktnummer ABIN6943152

Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch DUSP6 in WB, IF, ICC, FACS, IHC (p) und IHC (fro). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Rekombinanter DUSP6 Antikörper (AA 1-350) (ABIN6943152)

Target: DUSP6 (Dual Specificity Phosphatase 6 (DUSP6))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser DUSP6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-DUSP6 Antikörper

Bindungsspezifität: AA 1-350

Verwendungszweck: DUSP6 Recombinant Antibody

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: Recombinant protein within Human DUSP6 aa 1-350

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB(1:300-5000), IHC-P(1:200-400), IHC-F(1:100-500), IF(1:50-200), Flow-Cyt(1 μg/Test), ICC/IF(1:50-100)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: 0.01M TBS ( pH 7.4), 1 % BSA, 0.02 % Proclin 300, and 50 % Glycerol

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu DUSP6

Target: DUSP6 (Dual Specificity Phosphatase 6 (DUSP6))

Andere Bezeichnung: DUSP6

Hintergrund:

Synonyms: Dual specificity protein phosphatase 6, Dual specificity protein phosphatase PYST1, Mitogen-activated protein kinase phosphatase 3, MAP kinase phosphatase 3, MKP-3

Background: Inactivates MAP kinases. Has a specificity for the ERK family (PubMed:9858808). Plays an important role in alleviating chronic postoperative pain. Necessary for the normal dephosphorylation of the long-lasting phosphorylated forms of spinal MAPK1/3 and MAP kinase p38 induced by peripheral surgery, which drives the resolution of acute postoperative allodynia (By similarity). Also important for dephosphorylation of MAPK1/3 in local wound tissue, which further contributes to resolution of acute pain (By similarity).

Gen-ID: 1848

UniProt: Q16828

Pathways: Neurotrophin Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades