VEGFA Antikörper
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- Target Alle VEGFA Antikörper anzeigen
- VEGFA (Vascular Endothelial Growth Factor A (VEGFA))
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Reaktivität
- Human, Ratte, Maus, Hund, Kaninchen
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser VEGFA Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (IHC), Staining Methods (StM)
- Spezifität
- This MAb recognizes proteins of 19-22 kDa (reducing) and 38 kDa-44 kDa (non-reducing), identified as various isoforms of Vascular Endothelial Growth Factor or Vascular Permeability Factor (VEGF/VPF). It is highly specific to VEGF, which is a homodimeric, disulfide-linked glycoprotein with a close homology to platelet derived growth factor (PDGF). There are multiple isoforms of VEGF containing 206-, 189-, 165-, and 121-amino acid residues. The smaller two isoforms, VEGF165 and VEGF121, are secreted proteins and act as diffusible agents, whereas the larger two remain cell associated. VEGF/VPF plays an important role in angiogenesis, which promotes tumor progression and metastasis.
- Aufreinigung
- Purified by Protein A/G
- Immunogen
- Human VEGF189 recombinant protein
- Klon
- VEGF-1063
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product VEGFA Primärantikörper
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- Applikationshinweise
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Positive Control: Tumor cells in astrocytomas, breast or ovarian carcinomas.
Known Application: Immunohistochemistry (Formalin-fixed) (4-8 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 1 mM EDTA buffer, pH 8.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 200 μg/mL
- Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-80 °C
- Informationen zur Lagerung
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Haltbarkeit
- 24 months
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- Target
- VEGFA (Vascular Endothelial Growth Factor A (VEGFA))
- Andere Bezeichnung
- VEGFA (VEGFA Produkte)
- Synonyme
- MVCD1 antikoerper, VEGF antikoerper, VPF antikoerper, Vegf antikoerper, Vegf120 antikoerper, Vegf164 antikoerper, Vegf188 antikoerper, Vpf antikoerper, vegf antikoerper, vegfa antikoerper, wu:fj82c06 antikoerper, VEGF-A antikoerper, VEGF164 antikoerper, eVEGF120 antikoerper, eVEGF164 antikoerper, vegf-a antikoerper, vpf antikoerper, vefg antikoerper, si:dkey-14d8.3 antikoerper, wu:fd42e02 antikoerper, vascular endothelial growth factor A antikoerper, vascular endothelial growth factor Aa antikoerper, vascular endothelial growth factor A L homeolog antikoerper, vascular endothelial growth factor Ab antikoerper, VEGFA antikoerper, Vegfa antikoerper, vegfaa antikoerper, vegfa.L antikoerper, vegfa antikoerper, vegfab antikoerper
- Molekulargewicht
- 19-22kDa (reducing) and 38kDa-44kDa (non-reducing)
- Gen-ID
- 7422
- UniProt
- P15692
- Pathways
- RTK Signalweg, Glycosaminoglycan Metabolic Process, Regulation of Cell Size, Tube Formation, Signaling Events mediated by VEGFR1 and VEGFR2, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling
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