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PAX6 Antikörper (N-Term)

PAX6 Reaktivität: Human, Maus, Ratte, Huhn WB, IF, FACS Wirt: Maus Monoclonal PAX6-498 unconjugated
Produktnummer ABIN6940257
  • Target Alle PAX6 Antikörper anzeigen
    PAX6 (Paired Box 6 (PAX6))
    Bindungsspezifität
    • 26
    • 22
    • 16
    • 15
    • 10
    • 8
    • 6
    • 5
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-300, N-Term
    Reaktivität
    • 115
    • 71
    • 67
    • 14
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Huhn
    Wirt
    • 96
    • 39
    • 1
    Maus
    Klonalität
    • 86
    • 49
    Monoklonal
    Konjugat
    • 71
    • 8
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser PAX6 Antikörper ist unkonjugiert
    Applikation
    • 98
    • 50
    • 46
    • 40
    • 30
    • 26
    • 15
    • 14
    • 13
    • 9
    • 8
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)
    Spezifität
    Pax genes contain paired domains with strong homology to genes in Drosophila, which are involved in programming early development. Lesions in the Pax-6 gene account for most cases of aniridia, a congenital malformation of the eye, chiefly characterized by iris hypoplasia, which can cause blindness. Pax-6 is involved in other anterior segment malformations besides aniridia, such as Peters' anomaly, a major error in the embryonic development of the eye with corneal clouding with variable iridolenticulocorneal adhesions. The Pax-6 gene encodes a transcriptional regulator that recognizes target genes through its paired-type DNA-binding domain. The paired domain is composed of two distinct DNA-binding subdomains, the amino-terminal subdomain and the carboxy-terminal subdomain, which bind respective consensus DNA sequences. The human Pax-6 gene produces two alternatively spliced isoforms that have the distinct structure of the paired domain.
    Aufreinigung
    Purified by Protein A/G
    Immunogen
    Recombinant fragment (N-terminus, aa 1-300) of human PAX6 protein
    Klon
    PAX6-498
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product PAX6 Primärantikörper
  • Applikationshinweise

    Positive Control: Pancreas or Cerebellum.

    Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1 μg/mL), Western Blot (0.5-1 μg/mL), Optimal dilution for a specific application should be determined.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-80 °C
    Informationen zur Lagerung
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Haltbarkeit
    24 months
  • Target
    PAX6 (Paired Box 6 (PAX6))
    Andere Bezeichnung
    PAX6 (PAX6 Produkte)
    Synonyme
    pax6 antikoerper, an2 antikoerper, mgda antikoerper, wagr antikoerper, pax-6 antikoerper, pax6a antikoerper, xpax6 antikoerper, XLPAX6 antikoerper, MGC52531 antikoerper, PAX-6 antikoerper, AN antikoerper, AN2 antikoerper, D11S812E antikoerper, MGDA antikoerper, WAGR antikoerper, Pax-6 antikoerper, pax6b antikoerper, 1500038E17Rik antikoerper, AEY11 antikoerper, Dey antikoerper, Gsfaey11 antikoerper, Sey antikoerper, PAXZF-A antikoerper, Pax6.1 antikoerper, cb280 antikoerper, fc20e07 antikoerper, pax-a antikoerper, pax[zf-a] antikoerper, paxzfa antikoerper, wu:fc20e07 antikoerper, zfpax-6a antikoerper, zfpax-6b antikoerper, paired box 6 antikoerper, paired box 6 L homeolog antikoerper, paired box 6 S homeolog antikoerper, paired box 6a antikoerper, PAX6 antikoerper, pax6 antikoerper, Pax6 antikoerper, pax6.L antikoerper, pax6.S antikoerper, pax6a antikoerper
    Molekulargewicht
    47kDa
    Gen-ID
    5080
    UniProt
    P26367
    Pathways
    Peptide Hormone Metabolism, Carbohydrate Homeostasis
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