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MME Antikörper (AA 297-483)

This anti-MME antibody (ABIN6940061) is a Mouse Monoclonal antibody detecting MME in IHC, StM. Suitable for Human.
Produktnummer ABIN6940061

Kurzübersicht für MME Antikörper (AA 297-483) (ABIN6940061)

Target

Alle MME Antikörper anzeigen
MME (Membrane Metallo-Endopeptidase (MME))

Reaktivität

  • 222
  • 48
  • 43
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 119
  • 114
  • 2
  • 1
Maus

Klonalität

  • 143
  • 92
  • 2
Monoklonal

Konjugat

  • 145
  • 20
  • 17
  • 11
  • 7
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser MME Antikörper ist unkonjugiert

Applikation

  • 132
  • 103
  • 92
  • 63
  • 53
  • 47
  • 39
  • 17
  • 10
  • 8
  • 5
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Immunohistochemistry (IHC), Staining Methods (StM)

Klon

MME-1893
  • Bindungsspezifität

    • 10
    • 10
    • 8
    • 8
    • 8
    • 8
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 297-483

    Spezifität

    Recognizes a 100 kDa glycoprotein, identified as CD10, also known as Common Acute Lymphocytic Leukemia Antigen (CALLA). It is a cell surface enzyme with neutral metalloendopeptidase activity, which inactivates a variety of biologically active peptides. CD10 is expressed on the cells of lymphoblastic, Burkitt's, and follicular germinal center lymphomas, and on cells from patients with chronic myelocytic leukemia (CML). It is also expressed on the surface of normal early lymphoid progenitor cells, immature B cells within adult bone marrow and germinal center B cells within lymphoid tissue. CD10 is also present on breast myoepithelial cells, bile canaliculi, fibroblasts, with especially high expression on the brush border of kidney and gut epithelial cells.

    Aufreinigung

    Purified by Protein A/G

    Immunogen

    Recombinant human CD10 protein fragment (aa297-483) (exact sequence is proprietary)

    Isotyp

    IgG2b kappa
  • Applikationshinweise

    Positive Control: Tonsil, small intestine or kidney (IHC).

    Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    200 μg/mL

    Buffer

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-80 °C

    Informationen zur Lagerung

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    Haltbarkeit

    24 months
  • Target

    MME (Membrane Metallo-Endopeptidase (MME))

    Andere Bezeichnung

    MME

    Substanzklasse

    Chemical

    Molekulargewicht

    100kDa

    Gen-ID

    4311

    UniProt

    P08473

    Pathways

    RTK Signalweg, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration
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