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MCM7 Antikörper

MCM7 Reaktivität: Human WB, IHC, IF, FACS, StM Wirt: Maus Monoclonal SPM379 unconjugated
Produktnummer ABIN6940022
  • Target Alle MCM7 Antikörper anzeigen
    MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))
    Reaktivität
    • 116
    • 31
    • 26
    • 10
    • 9
    • 8
    • 7
    • 7
    • 3
    • 2
    • 1
    Human
    Wirt
    • 77
    • 37
    • 2
    Maus
    Klonalität
    • 69
    • 47
    Monoklonal
    Konjugat
    • 75
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MCM7 Antikörper ist unkonjugiert
    Applikation
    • 79
    • 37
    • 36
    • 27
    • 21
    • 18
    • 17
    • 12
    • 12
    • 12
    • 5
    • 4
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Staining Methods (StM)
    Aufreinigung
    Purified by Protein A/G
    Immunogen
    Recombinant human hCDC47 protein
    Klon
    SPM379
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product MCM7 Primärantikörper
  • Applikationshinweise

    Positive Control: Exponentially growing any cultured human cells. Tonsil or lymph node.

    Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1 μg/mL), Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-80 °C
    Informationen zur Lagerung
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Haltbarkeit
    24 months
  • Target
    MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))
    Andere Bezeichnung
    MCM7 (MCM7 Produkte)
    Hintergrund
    MCM7 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that is essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumor suppressor protein RB1/RB.
    Molekulargewicht
    88kDa
    Gen-ID
    4176
    UniProt
    P33993
    Pathways
    DNA Reparatur, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
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