Rekombinanter Prostate Specific Antigen Antikörper

Produktnummer ABIN6939775

Dieses Anti-Prostate Specific Antigen-Antikörper ist ein Kaninchen Monoklonal-Antikörper zur Detektion von Prostate Specific Antigen in IHC, StM und ISt. Geeignet für Human.

Kurzübersicht für Rekombinanter Prostate Specific Antigen Antikörper (ABIN6939775)

Target: Prostate Specific Antigen (PSA)

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Prostate Specific Antigen Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Staining Methods (StM), Immunostaining (ISt)

Klon: KLK3-2871R

Produktdetails anti-Prostate Specific Antigen Antikörper

Spezifität: Recognizes a single protein of 33-34 kDa, identified as the prostate specific antigen (PSA). This MAb is highly specific to PSA and stains prostatic secretory and ductal epithelium in both normal and neoplastic tissues. PSA is a chymotrypsin-like serine protease (kallikrein family) exclusively produced by the prostate epithelium, and abundant in seminal fluid. PSA can be detected in the sera of patients with prostatic carcinoma. It is predominantly complexed to a liver-derived serine protease inhibitor, alpha-1-antichymotrypsin (ACT). A higher proportion of serum PSA is complexed to ACT in prostate cancer than in benign prostate hyperplasia. This MAb makes an excellent pair with MAb A67-B/E3 for PSA tests.

Aufreinigung: Purified by Protein A/G

Immunogen: Recombinant full-length human KLK3 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Positive Control: PC12 cells. Normal prostate or prostate carcinoma.

Known Application: Immunohistochemistry (Formalin-fixed) (0.5-1.0 μg/mL for 30 minutes at RT) (Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0 for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu Prostate Specific Antigen

Target: Prostate Specific Antigen (PSA)

Andere Bezeichnung: KLK3

Molekulargewicht: 33-34kDa

Gen-ID: 354

UniProt: P07288

Pathways: Komplementsystem