HLA-ABC Antikörper

Produktnummer ABIN6939617

Dieses Maus Monoklonal-Antikörper erkennt spezifisch HLA-ABC in FACS und IF. Er zeigt eine Reaktivität gegenüber Human, Maus und Non-Human Primate.

Kurzübersicht für HLA-ABC Antikörper (ABIN6939617)

Target: HLA-ABC

Reaktivität: Human, Maus, Non-Human Primate

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser HLA-ABC Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF)

Klon: 246-B8-E7

Produktdetails anti-HLA-ABC Antikörper

Spezifität: Reacts with a monomorphic determinant of human major histocompatibility (MHC) class I antigens (HLA-A, B and C). Human MHC class I antigens are expressed constitutively on all nucleated cells lymphocytes such as lymphocytes, thymocytes, granulocytes, and bone marrow cells and are absent on erythrocytes. MHC class I antigens play a role in class I MHC-associated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance, and tissue allotransplantation.

Aufreinigung: Purified by Protein A/G

Immunogen: Human peripheral blood leukocytes

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise:

Positive Control: THP-1 and Jurkat cells. Tonsil or lymph node.

Known Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu HLA-ABC

Target: HLA-ABC

Andere Bezeichnung: HLA-A, HLA-B, HLA-C

Molekulargewicht: ~41kDa

Gen-ID: 3105, 3106, 3107

UniProt: P01889, P30443, P30499

Pathways: T-Zell Rezeptor Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints