TGFA Antikörper (C-Term)
Kurzübersicht für TGFA Antikörper (C-Term) (ABIN6938542)
Target
Alle TGFA Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- C-Term
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Spezifität
- This antibody reacts with the C-terminus of TGF alpha and shows no cross-reaction with EGF and the neuropeptide synenkephalin. The staining with Ab-1 is completely blocked by the peptide used for raising this antibody. TGF (aa50) is a growth factor with 33 % homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.
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Kreuzreaktivität (Details)
- Human. Cow. Rat. Mouse.
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Aufreinigung
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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Immunogen
- A 17-amino acid synthetic peptide from the carboxyl-terminus of rat TGFα.
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Isotyp
- IgG1 kappa
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Applikationshinweise
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.
Positive_Control: Jurkat or Ramos cells. Testicular Carcinoma.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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Konservierungsmittel
- Azide free
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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Haltbarkeit
- 24 months
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- TGFA (Transforming Growth Factor, alpha (TGFA))
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Andere Bezeichnung
- TGFA
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Hintergrund
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EGF-like TGF, ETGF, TFGA, TGF Type 1, TGFA, Wa1, Waved 1,TGF-alpha (Transforming Growth Factor alpha)
Cellular localisation: Cytoplasmic and Extracellular (secreted) -
Molekulargewicht
- ~6kDa
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Gen-ID
- 7039, 170009
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UniProt
- P01135
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Pathways
- NF-kappaB Signalweg, RTK Signalweg, EGFR Signaling Pathway
Target
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