TCF4 Antikörper (AA 365-671)
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- Target Alle TCF4 Antikörper anzeigen
- TCF4 (Transcription Factor 4 (TCF4))
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Bindungsspezifität
- AA 365-671
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser TCF4 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Coating (Coat), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Spezifität
- Recognizes a protein of 71kDa, identified as Transcription Factor 4 (TCF4). It is a basic helix-loop-helix transcription factor. The encoded protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. This gene is broadly expressed and may play an important role in nervous system development. Defects in this gene are a cause of Pitt-Hopkins syndrome.
- Kreuzreaktivität (Details)
- Human.
- Aufreinigung
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- Recombinant human TCF4 protein fragment (around aa 365-671) (exact sequence is proprietary)
- Klon
- TCF4-1705
- Isotyp
- IgG2a kappa
- Top Product
- Discover our top product TCF4 Primärantikörper
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- Applikationshinweise
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Known_Application: ELISA (For coating, order antibody without BSA), ,Western Blot (1-2 μg/mL), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: HeLa or HepG2 cells. Human bladder, colon or tonsil.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Konservierungsmittel
- Azide free
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Haltbarkeit
- 24 months
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- Target
- TCF4 (Transcription Factor 4 (TCF4))
- Andere Bezeichnung
- TCF4 (TCF4 Produkte)
- Synonyme
- E2-2 antikoerper, ITF-2 antikoerper, ITF2 antikoerper, PTHS antikoerper, SEF-2 antikoerper, SEF2 antikoerper, SEF2-1 antikoerper, SEF2-1A antikoerper, SEF2-1B antikoerper, TCF-4 antikoerper, bHLHb19 antikoerper, 5730422P05Rik antikoerper, ASP-I2 antikoerper, E2.2 antikoerper, ITF-2b antikoerper, ME2 antikoerper, MITF-2A antikoerper, MITF-2B antikoerper, TFE antikoerper, Tcf-4 antikoerper, TCF7L2 antikoerper, XE2 antikoerper, Xtcf-4 antikoerper, Xtcf4 antikoerper, e2-A antikoerper, tcf-4 antikoerper, transcription factor 4 antikoerper, transcription factor 4 S homeolog antikoerper, TCF4 antikoerper, Tcf4 antikoerper, tcf4 antikoerper, tcf4.S antikoerper
- Hintergrund
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BHLHb19, Class B basic helix-loop-helix protein 19, Immunoglobulin transcription factor 2, ITF-2, PTHS, SEF2, SL3-3 enhancer factor 2, TCF4, Transcription factor 4,TCF4 (Transcription Factor 4)
Cellular localisation: Nucleus. Cytoplasm. - Molekulargewicht
- 60kDa
- Gen-ID
- 6925, 605153
- UniProt
- P15884
- Pathways
- WNT Signalweg, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Regulation of Hormone Metabolic Process, Carbohydrate Homeostasis, Stem Cell Maintenance, Protein targeting to Nucleus
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