NADPH Oxidase 4 Antikörper
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- Target Alle NADPH Oxidase 4 (NOX4) Antikörper anzeigen
- NADPH Oxidase 4 (NOX4)
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser NADPH Oxidase 4 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Coating (Coat)
- Spezifität
- The superoxide-generating NADPH oxidase includes a membrane-bound flavocytochrome containing two subunits, gp91-phox and p22-phox, and the cytosolic proteins p47-phox and p67-phox. During activation of the NADPH oxidase, p47-phox and p67-phox migrate to the plasma membrane where they associate with the flavocytochrome, cytochrome b558, to form the active enzyme complex. The p22 and gp91-phox subunits also function as surface O2 sensors that initiate cellular signaling in response to hypoxic conditions. NOX4 is a renal gp91-phox homolog highly expressed at the site of erythropoietin production in the proximal convoluted tubule epithelial cells of the renal cortex. It is also expressed in fetal tissues, placenta, glioblastoma and vascular cells.
- Kreuzreaktivität (Details)
- Human.
- Aufreinigung
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- Recombinant human NOX4 protein
- Klon
- NOX4-1245
- Isotyp
- IgG2b kappa
- Top Product
- Discover our top product NOX4 Primärantikörper
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- Applikationshinweise
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Known_Application: ELISA (For coating, order Ab without BSA)Western Blot (1-2 μg/mL), Optimal dilution for a specific application should be determined.
Positive_Control: PC-12, JAR cells. Kidney.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Konservierungsmittel
- Azide free
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Haltbarkeit
- 24 months
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- Target
- NADPH Oxidase 4 (NOX4)
- Andere Bezeichnung
- NOX4 (NOX4 Produkte)
- Synonyme
- KOX antikoerper, KOX-1 antikoerper, RENOX antikoerper, AI648021 antikoerper, nox4 antikoerper, NOX4 antikoerper, NADPH oxidase 4 antikoerper, NOX4 antikoerper, Nox4 antikoerper, nox4 antikoerper, PTRG_09562 antikoerper
- Hintergrund
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Kidney oxidase-1, Kidney superoxide-producing NADPH oxidase, KOX-1, NADPH oxidase 4, Nox4, Renal NAD(P)H-oxidase, RENOX,NOX4 / NADPH Oxidase 4
Cellular localisation: Cytoplasm and Cell Surface - Molekulargewicht
- 70kDa
- Gen-ID
- 50507, 371036
- UniProt
- Q9NPH5
- Pathways
- Carbohydrate Homeostasis, Smooth Muscle Cell Migration
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